One-pot and catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates†

dc.contributor.author	Zhang, Xiaofenga
dc.contributor.author	Dhawan, Gagan
dc.contributor.author	Muthengi, Alex
dc.contributor.author	Liu, Shuai
dc.contributor.author	Wang, Wei
dc.contributor.author	Legrisa, Marc
dc.contributor.author	Zhang, Wei
dc.date.accessioned	2021-11-09T07:35:27Z
dc.date.available	2021-11-09T07:35:27Z
dc.date.issued	2017
dc.identifier.citation	This journal is © The Royal Society of Chemistry	en_US
dc.identifier.uri	http://repository.tharaka.ac.ke/xmlui/handle/1/3173
dc.description.abstract	A method for the catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates is develo ped through a one-pot synthesis involving denitrogenation of azide, benzisoxazole formation, aza-Diels– Alder cycloaddition, and dehydrative aromatization. Only stoichiometric amounts of N2 and H2O are pro duced as by-products. A comprehensive green chemistry metrics analysis indicated that this method is much more efficient and greener than two reported methods for the synthesis of pyrroloquinolinediones.	en_US
dc.language.iso	en_US	en_US
dc.title	One-pot and catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates†	en_US
dc.type	Article	en_US